Women Often Get Drugs With High Fetal Risk

Women are often unaware that the drugs they take may lead to birth defects.

ByABC News
September 17, 2007, 5:21 PM

Sept. 18, 2007 — -- Women of childbearing age may unknowingly take drugs that could cause birth defects in fetuses that's a significant finding, considering that up to half of all pregnancies are unplanned.

A new study, published in the journal Annals of Internal Medicine, suggests that doctors should be more diligent in counseling their patients about these possible effects and prescribing birth control when necessary.

"A lot of times, women assume that their doctors will tell them everything they need to know," said lead author Dr. Eleanor Schwarz, assistant professor of obstetrics, gynecology and reproductive science at the University of Pittsburgh.

"Women need to be empowered to ask for information, because sometimes, information is being overlooked that is relevant to their decisions about when they are going to pursue a family."

Other doctors agree that physicians must take special care when prescribing these drugs to women in their childbearing years.

"Many doctors don't know the pregnancy categories of the drugs they are prescribing," said Dr. Lisa Jones, an OB-GYN with the Greater New Bedford Community Health Center in Massachusetts.

Currently, the U.S. Food and Drug Administration categorizes drugs into five different groups.

Class A and B drugs are generally thought to be OK for women to take during pregnancy.

For drugs in class C, there is not enough evidence to determine fetal risk.

Class D drugs have been shown to cause harm to the fetus, but in some cases, the benefits of taking the drugs may outweigh the risks.

Meanwhile, Class X drugs are harmful to the fetus and should not be taken during pregnancy.

The study looked at nearly half a million women of childbearing age and discovered that one in six had obtained a class D or X drug from their pharmacist, but only half of these women were counseled on contraception at the time the prescription was given.

According to the study, 1 percent of women taking class D or X drugs became pregnant within three months of starting the medication.